More or Less: IV Epinephrine in Cardiac Arrest
- David Arbona, MD
- Jun 18, 2024
- 1 min read
The more Epinephrine in cardiac arrest, the better right?
Ok, we know many of you don't believe that.
By now many EMS agencies have limited Epinephrine dosing in cardiac arrest to 3 mg. Some have even limited it to 1 mg.
A recent study looked at total Epi dosing, specifically in patients receiving eCPR ! 🚑💉
📊 Key Takeaways from the Study:
➡ Researchers classified patients into low (≤3 mg) and high (>3 mg) epinephrine dosage groups.
âž¡ Patients with a lower epinephrine dose had better neurological outcomes at hospital discharge (55%) compared to the high-dose group (24%).
âž¡ Higher doses correlated with unfavorable neurological outcomes, with an adjusted odds ratio of 4.6 for poor results, underscoring potential risks of high cumulative doses.
🧠Conclusions:
âž¡ Higher cumulative doses of epinephrine (>3 mg) might be linked to worse neurological outcomes post-ECPR.
âž¡ This data suggests reevaluating epinephrine dosing during resuscitation, especially considering the potential for adverse neurological impacts.
Interested in the details or have insights to share from your experiences? 📚 Read the full study here https://ow.ly/XMOw50Roa6w and let's discuss how we can optimize our care for the best patient outcomes!
